NIH Research Matters

June 3, 2025 Edition

Infant with rare disease receives customized gene therapy

Researchers used a personalized gene-editing approach to mend a faulty gene in a baby born with a rare, often deadly disorder.

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Researchers describe cancer trends in people under 50

May 20, 2025 — A nationwide analysis found a higher incidence of 14 types of cancer among people under 50 years old compared to rates in 2010.
Gauging biological age to predict future health

May 20, 2025 — Researchers developed a tool to quantify various aspects of a person’s biological age and health status.
Brain circuit rewiring during motor learning

May 20, 2025 — A new study in mice sheds light on how brain circuits get rewired when learning new movements.
Involuntary responses reflect severity of tinnitus symptoms

May 13, 2025 — By analyzing subtle facial movements, researchers found ways to objectively measure the severity of tinnitus and sound sensitivity disorder symptoms.
Disrupting fat metabolism may hinder pancreatic cancer

May 13, 2025 — Scientists were able to target a fat-recycling process to reduce pancreatic tumors in mouse and human models.
Scientists find subtypes of senescence

May 13, 2025 — Researchers found that cells in skin that stop dividing but don’t die, called senescent cells, aren’t all the same, coming in three types with distinct treatment responses.
Smoking cessation pill may help youth quit vaping

May 6, 2025 — Teens and young adults who took a smoking cessation drug called varenicline were more likely to quit vaping nicotine than those who got a placebo pill.
Decoding how nerves sense heat and pain

May 6, 2025 — A study in mice yielded new insights into the workings of nerve cells that sense touch and temperature from the skin, and how inflammation leads to pain.
An LSD analogue for treating psychiatric diseases

May 6, 2025 — Researchers designed a non-hallucinogenic analogue of LSD that had antidepressant and numerous cognitive benefits in mice.
Brain-computer interface restores natural speech after paralysis

April 29, 2025 — Researchers developed a brain-computer interface that quickly translates brain activity into audible words.

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Research in Context

In-depth articles that focus on cutting-edge NIH biomedical research topics, describing the current state of research in a field and where it may be heading.

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About NIH Research Matters

Editor: Harrison Wein, Ph.D.

Assistant Editors: Vicki Contie and Brian Doctrow, Ph.D.

NIH Research Matters is a weekly update of NIH research highlights reviewed by NIH’s experts. It's published by the Office of Communications and Public Liaison in the NIH Office of the Director.

ISSN 2375-9593

This page last reviewed on April 15, 2025

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